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The four trials that measured sleep efficiency found no benefit of trazodone over placebo. This drug is not FDA approved for use in pediatric patients or for treatment of bipolar depression with or without episodes of anxiety; This medication contains trazodone Do not take Desyrel, Desyrel Dividose, Oleptro, or Trazodone D, if you are allergic to trazodone or any ingredients contained in this drug; Keep out of reach of children. 1. 2.   Use trazodone with caution if you have heart or cerebrovascular disease, seizures, or kidney or liver problems. Though it can work, should you take trazodone for insomnia? Trazodone (trade name Desyrel) is a very old antidepressant of the Tricyclic class.Trazodone is actually not an antipsychotic due to the fact that it has no effects on Dopamine or Epinephrine. It comes as an oral tablet and as a generic drug only. Three trials reported on perceived sleep quality, which was significantly better with trazodone than with placebo. Bipolar disorder is primarily about manic symptoms. Learn about side effects, warnings, dosage, and more. It should be noted that trazodone is not approved for use in treating bipolar depression. Trazodone also has limitations. Trazodone makes you feel drowsy, and when taken before going to bed it can help you to drop off to sleep. MAOI therapy Due to the risk for serotonin syndrome, it is recommended that trazodone not be used in combination with monoamine oxidase inhibitor therapy (MAOI therapy) or within 14 days of discontinuing treatment with an MAOI. “Trazodone helped me so much, I felt a boost in my confidence, I slept better at nights and my energy levels were so high. It's been over a year since this post, and even though I hate to bump an old thread, I thought this deserved an update. Its sedative effects tend to wear off over time, and it comes with risks including daytime fatigue, reduced recovery rates in depression (a paradoxical phenomenon seen in adolescents), 1 and dry mouthâ which itself may interfere with sleep. I felt so great everyday when I took them, I would always take them 9pm at night, then get tired half an hour after taking them. If you have trouble falling asleep, you should take your Trazodone about three hours before bedtime. There are two misconceptions that must be clarified: 1. Trazodone is a prescription drug for treating depression. 5.3 Screening Patients for Bipolar Disorder and Monitoring for Mania/ Hypomania A major depressive episode may be the initial presentation of bipolar disorder. Trazodone may also not be appropriate for people who have psychiatric illnesses, including bipolar disease and schizophrenia, as well as in those at risk for suicide. Bipolar medications address the full spectrum of bipolar symptoms. Trazodone is non-addictive, and it is quite inexpensive, which make it a popular choice for doctors to prescribe. The concomitant use of trazodone hydrochloride tablets with serotonin precursors (such as tryptophan) is not recommended. For example, bipolar depression symptoms are over three times more common than bipolar mania. Trouble Falling Asleep. SSRIs can provoke weight gain over time. Trazodone is a widely used but little-known drug prescribed off-label to treat insomnia, Consumer Reports notes. It definitely helped with sleep. Trazodone did not. I was ready for the day at 7am. Find patient medical information for trazodone oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. SSRIs produce a lot of sexual side effects, blocking ejaculation and erection. Trial participants randomized to receive trazodone took the drug for a mean 1.7 weeks in doses ranging from 50 to 150 mg/day. 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